In cases where your machine can only access the HFS Backup service over VPN and the bandwidth restrictions are preventing you from completing a backup of a large amount of valuable data, then we would cautiously sanction the use of OneDrive as an offsite store.
Be aware, however, that Microsoft is careful to describe OneDrive as a File Sync and Share service not as a backup solution. The distinction may be subtle, but remember that changes to a file or document in the cloud will be propagated back down to your local device, as well as the more intuitive syncing of changes from local device up to the cloud copy. There are other distinctions that make, for example, restoring files from deleted folders and point-in-time restores challenging.
Be aware also that there is a 5TB limit per user for OneDrive storage.